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Symbol
Name
ID
Casp9
caspase 9
MGI:1277950
Phenotype annotations related to nervous system
Darker colors indicate more annotations
Human Phenotypes
Hyposmia
Anorexia
Spasticity
Bradykinesia
Tremor
Depression
Anxiety
Panic attack
Hallucinations
Apathy
Reduced social reciprocity
Impulsivity
Agitation
Restless legs
Cognitive impairment
Dementia
Frontal lobe dementia
Short attention span
Insomnia
Hyperreflexia
Dyskinesia
Dystonia
Gait imbalance
Postural instability
Abnormal autonomic nervous system physiology
Disease(s) Associated with CASP9
pancreatic cancer
Parkinson's disease

Mouse Phenotypes
intracerebral hemorrhage
decreased neuron apoptosis
abnormal embryonic neuroepithelial layer differentiation
abnormal lamina terminalis morphology
abnormal neural tube closure
abnormal brain morphology
abnormal brain development
abnormal forebrain development
abnormal telencephalon development
abnormal midbrain-hindbrain boundary morphology
hydrocephaly
increased midbrain size
abnormal brain ventricle morphology
abnormal lateral ventricle morphology
abnormal third ventricle morphology
brain ventricle stenosis
abnormal brain commissure morphology
absent corpus callosum
abnormal telencephalon morphology
abnormal cerebral hemisphere morphology
abnormal cerebral cortex morphology
exencephaly
Availability Mouse Genotype
Casp9tm1Flv/Casp9tm1Flv
Casp9tm1Mak/Casp9tm1Mak

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory